Fibromyalgia (FM) is a frequently encountered disorder with challenging diagnosis and treatment, fibromyalgia (FM) affects up to 10% of general population mostly women.
FM is defined by chronic widespread pain usually accompanied by other symptoms including anxiety/depressive symptoms, fatigue, sleep disturbances, cognitive dysfunction, and headache that impair the quality
of life .
The guidelines used for therapy and prevention of FM symptoms includes antidepressants such as SSRI or SNRI (serotonin alone or serotonin and noradrenalin reuptake inhibitors), GABA stimulating agents, cannabinoids, anti-oxidants and anti-inflammatory agents.
Naveh pharma developed FIBROMAG, An innovative, natural and unique supplement, composed of herbal extracts vitamin and minerals. Fibromag ingredients have a multifunctional effect that conforms to the guideline used as FM treatment containing both natural antidepressants, GABA stimulation endocannabinoid, anti-inflammatory agents and anti-oxidants. FIBROMAG, based on Saffron, pharmaceutical patented extract, Magnox, unique patented and most bioavailable form of magnesium as well as Vitamins B12, B6, D and Folic acid. (Magnesium and vitamins B6, B12, and D are common vitamin deficiencies found in fibromyalgia patients). Fibromag is the ultimate supplement for the prevention of Fibromyalgia and its related unbearable symptoms.
The Logic behind the Ingredients
Saffron – Natural Antidepressant, Anti-Inflammatory and Cannabinoid effect
Saffron (Crocus sativus L.), is a novel interesting candidate for treatment of FM since its benefits in several medical conditions, including depression. In particular, saffron was found beneficial in clinical trials of depressive disorders and anxiety as well as in chronic pain.
Magnesium - Relieve Fatigue, Reduction of Fibromyalgia Symptoms Magnesium has long been investigated as a possible treatment for fibromyalgia.
Magnesium can temper the inflammation that drives the syndrome, relieve fatigue by increasing ATP production, generate cellular energy in the form of adenosine triphosphate (ATP), which has been called the “energy currency of life.” A study at the Mayo Clinic in Minnesota confirmed existing medical research, which says that maintaining therapeutic serum magnesium levels has been linked to a lowering of fibromyalgia symptoms including depression, tender point score, and fatigue.
Vitamin B6 – precursor to the metabolism of neurotransmitters Vitamin B6 is used for the metabolism of neurotransmitters. Neurotransmitters imbalances, lead to fibromyalgia, depression, and/or anxiety. Therefore, Vitamin B6, is crucial and its deficiency can contribute to fibromyalgia. Vitamin B6, lower homocysteine levels.
Vitamin B12 - balancing iron levels, promotes metabolism of neurotransmitters Vitamin B12 support a true positive response in studied group of patients with fibromyalgia probably by balancing ferritin(8) and iron levels as well as its importance in the metabolism of neurotransmitters. Vitamin B12 lowers homocysteine levels.
Vitamin D - improving physical functioning In a clinical study, the treatment group showed improved physical functioning, had less morning fatigue than the placebo group and reported a marked reduction in pain.
Folat– precursor to neurotransmitters metabolism, reduces homocysteine.
Folat is the precursor to the metabolism of neurotransmitters. Neurotransmitters imbalances, lead to fibromyalgia, depression, and/or anxiety. Patients with Fibromyalgia diagnosed with high level of homocysteine. Folic acid lower homocysteine levels.